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010 _a2015014810
020 _a9789814670241
_c148.05 SAR
020 _a9814670243
020 _a0071830936 (print-ISBN)
020 _a9780071830935 (print-ISBN)
035 _a(OCoLC)907515796
040 _aSA-DaMAC
_cSA-DaMAC
050 4 _aRM301.4
_b.L46 2016
060 1 0 _aQV 38
082 0 4 _a615.7
_223
100 1 _aShargel, Leon,
_d1941-,
_eath.
245 1 0 _aApplied biopharmaceutics & pharmacokinetics
_h[electronic resource] /
_cLeon Shargel, Andrew B.C. Yu.
246 3 0 _aApplied biopharmaceutics and pharmacokinetics
250 _a7th ed.
260 _aNew York, N.Y. :
_bMcGraw-Hill Education LLC.,
_cc2016.
300 _a1 online resource :
_bill., figs., tables.
490 1 _aMcGraw-Hill's AccessPharmacy
500 _a"Previous editions copyright ©2012 by The McGraw-Hill Companies, Inc.; ©2005, 1999, 1993 by Appleton & Lange; ©1985, 1980 by Appleton-Century-Crofts.".
504 _aIncludes bibliographical references and indexes.
505 0 _aChapter 1: Introduction to Biopharmaceutics and Pharmacokinetics -- Chapter 2: Mathematical Fundamentals in Pharmacokinetics -- Chapter 3: Biostatistics -- Chapter 4: One-Compartment Open Model: Intravenous Bolus Administration -- Chapter 5: Multicompartment Models: Intravenous Bolus Administration -- Chapter 6: Intravenous Infusion -- Chapter 7: Drug Elimination, Clearance, and Renal Clearance -- Chapter 8: Pharmacokinetics of Oral Absorption -- Chapter 9: Multiple-Dosage Regimens -- Chapter 10: Nonlinear Pharmacokinetics -- Chapter 11: Physiologic Drug Distribution and Protein Binding -- Chapter 12: Drug Elimination and Hepatic Clearance -- Chapter 13: Pharmacogenetics and Drug Metabolism -- Chapter 14: Physiologic Factors Related to Drug Absorption -- Chapter 15: Biopharmaceutic Considerations in Drug Product Design and In Vitro Drug Product Performance -- Chapter 16: Drug Product Performance, In Vivo: Bioavailability and Bioequivalence -- Chapter 17: Biopharmaceutical Aspects of the Active Pharmaceutical Ingredient and Pharmaceutical Equivalence -- Chapter 18: Impact of Biopharmaceutics on Drug Product Quality and Clinical Efficacy -- Chapter 19: Modified-Release Drug Products and Drug Devices -- Chapter 20: Targeted Drug Delivery Systems and Biotechnological Products -- Chapter 21: Relationship Between Pharmacokinetics and Pharmacodynamics -- Chapter 22: Application of Pharmacokinetics to Clinical Situations -- Chapter 23: Application of Pharmaco­kinetics to Specific Populations: Geriatric, Obese, and Pediatric Patients -- Chapter 24: Dose Adjustment in Renal and Hepatic Disease -- Chapter 25: Empirical Models, Mechanistic Models, Statistical Moments, and Noncompartmental Analysis -- Appendix A: Applications of Software Packages in Pharmacokinetics -- Appendix B: Glossary.
520 3 _aThe landmark textbook on the theoretical and practical applications of biopharmaceutics and pharmacokinetics-now fully updated.
530 _aAlso issued in online and PDF version.
588 _aDescription based on cover image and table of contents, viewed on Oct. 24, 2016.
650 0 _aBiopharmaceutics.
650 0 _aPharmacokinetics.
650 1 2 _aBiopharmaceutics.
650 2 2 _aModels, Chemical.
650 2 2 _aPharmacokinetics.
700 1 _aYu, Andrew B. C.,
_d1945-
_eed.
776 0 8 _iOnline version:
_tApplied biopharmaceutics & pharmacokinetics.
_bSeventh edition.
_dNew York, N.Y. : McGraw-Hill Education LLC.,
_c2016.
_w(OCoLC)907515796
830 0 _aMcGraw-Hill's AccessPharmacy.
856 4 0 _uhttp://accesspharmacy.mhmedical.com/book.aspx?bookID=1592
942 _2lcc
_cBK
999 _c1524
_d1524