TY  - BOOK
AU  - Ritschel,W.A.
AU  - Kearns,Gregory L.
ED  - American Pharmaceutical Association.
TI  - Handbook of basic pharmacokinetics-- including clinical applications
SN  - 1582120544
AV  - RM301.5 .R57 2004
U1  - 615.7 22
PY  - 2004///
CY  - Washington, D.C.
PB  - American Pharmacists Association
KW  - Pharmacokinetics
KW  - Handbooks, manuals, etc
KW  - Clinical pharmacology
KW  - Pharmacocinétique
KW  - Guides, manuels, etc
KW  - Pharmacologie clinique
KW  - fast
KW  - Farmacocinética
KW  - larpcal
KW  - Handbooks
KW  - Handbooks and manuals
N1  - Includes bibliographical references and index; Definitions and glossary -- The LADMER system: liberation, absorption, distribution, metabolism, elimination, and response -- Organs, tissues, cells, and organelles -- Cell membranes -- Drug-receptor interactions -- Absorption/transport mechanisms -- pKa and degree of ionization -- Lipid/water partition coefficient -- Physicochemical factors altering biological performance of drugs -- Biopharmaceutical data of the gastrointestinal tract -- Fluid compartments and circulatory system -- Binding of drugs to biological material -- Drug biotransformation -- Compartment models -- Determination of rate constants -- Volume of distribution and distribution coefficient -- Excretion and clearance of drugs -- Urinary and biliary recycling; Cumulative urinary excretion -- Area under the blood level-time curve -- Pharmacokinetics of single dose administration -- Pharmacokinetics of multiple dosing -- Compartment model independent analysis -- Pediatric pharmacokinetics -- Drug dosage in elderly patients -- Drug dosage in obese patients -- Drug disposition in pregnancy -- Dosage regimen design -- Drug monitoring and dosage adjustment -- Physiological and pathological factors influencing drug response -- First dosage size in man -- Forensic pharmacokinetics -- Nonlinear pharmacokinetics -- Curve fitting -- Correlation of clinical response with drug disposition -- Bioavailability and bioequivalence -- Body surface areas -- Extracorporeal methods of drug removal -- Pharmacogenetics and pharmacogenomics
N2  - A user-friendly handbook on the principles and techniques involved in the various applications of pharmacokinetics. Provides a concise reference for clinicians who need quick information on the pharmacokinetic characteristics of specific drugs. Thoroughly updated and revised, this book features pharmacokinetic data profiles on more than 600 drugs
UR  - http://catdir.loc.gov/catdir/toc/ecip0412/2003026662.html
UR  - http://www.e-streams.com/es0712/es0712_3810.html
UR  - http://catdir.loc.gov/catdir/description/mh041/2003026662.html
ER  -