TY - BOOK AU - Shargel,Leon AU - Yu,Andrew B.C. TI - Applied biopharmaceutics & pharmacokinetics T2 - McGraw-Hill's AccessPharmacy SN - 9789814670241 AV - RM301.4 .L46 2016 U1 - 615.7 23 PY - 2016/// CY - New York, N.Y. : PB - McGraw-Hill Education LLC., KW - Biopharmaceutics KW - Pharmacokinetics KW - Models, Chemical N1 - "Previous editions copyright ©2012 by The McGraw-Hill Companies, Inc.; ©2005, 1999, 1993 by Appleton & Lange; ©1985, 1980 by Appleton-Century-Crofts."; Includes bibliographical references and indexes; Chapter 1: Introduction to Biopharmaceutics and Pharmacokinetics -- Chapter 2: Mathematical Fundamentals in Pharmacokinetics -- Chapter 3: Biostatistics -- Chapter 4: One-Compartment Open Model: Intravenous Bolus Administration -- Chapter 5: Multicompartment Models: Intravenous Bolus Administration -- Chapter 6: Intravenous Infusion -- Chapter 7: Drug Elimination, Clearance, and Renal Clearance -- Chapter 8: Pharmacokinetics of Oral Absorption -- Chapter 9: Multiple-Dosage Regimens -- Chapter 10: Nonlinear Pharmacokinetics -- Chapter 11: Physiologic Drug Distribution and Protein Binding -- Chapter 12: Drug Elimination and Hepatic Clearance -- Chapter 13: Pharmacogenetics and Drug Metabolism -- Chapter 14: Physiologic Factors Related to Drug Absorption -- Chapter 15: Biopharmaceutic Considerations in Drug Product Design and In Vitro Drug Product Performance -- Chapter 16: Drug Product Performance, In Vivo: Bioavailability and Bioequivalence -- Chapter 17: Biopharmaceutical Aspects of the Active Pharmaceutical Ingredient and Pharmaceutical Equivalence -- Chapter 18: Impact of Biopharmaceutics on Drug Product Quality and Clinical Efficacy -- Chapter 19: Modified-Release Drug Products and Drug Devices -- Chapter 20: Targeted Drug Delivery Systems and Biotechnological Products -- Chapter 21: Relationship Between Pharmacokinetics and Pharmacodynamics -- Chapter 22: Application of Pharmacokinetics to Clinical Situations -- Chapter 23: Application of Pharmaco­kinetics to Specific Populations: Geriatric, Obese, and Pediatric Patients -- Chapter 24: Dose Adjustment in Renal and Hepatic Disease -- Chapter 25: Empirical Models, Mechanistic Models, Statistical Moments, and Noncompartmental Analysis -- Appendix A: Applications of Software Packages in Pharmacokinetics -- Appendix B: Glossary; Also issued in online and PDF version N2 - The landmark textbook on the theoretical and practical applications of biopharmaceutics and pharmacokinetics-now fully updated UR - http://accesspharmacy.mhmedical.com/book.aspx?bookID=1592 ER -